WebNov 3, 2024 · Results At current drug pricing, the estimated additional cost of a 10-day course of fidaxomicin compared to vancomycin in order to prevent one recurrence was $46,178USD (95%CI $36,942-$69,267) and $13,760CAD (95%CI $11,008-$20,640), respectively. The estimated mean systemic cost of a CDI recurrence was $14,506USD … WebFidaxomicin plasma levels were increased, but not clinically significant. According to prescribing information, dose reductions are not recommended when fidaxomicin is administered with cyclosporine or other P-gp inhibitors. Acquisition Costs. Listed below are the Federal Supply Schedule costs per day and per 10 day treatment of CDAD treatment ...
Optimer Pharmaceuticals Provides Update on DIFICID® (fidaxomicin …
WebMay 31, 2024 · Fidaxomicin had a 13.5% higher rate of 4-week sustained response compared to vancomycin and 13.2% higher rate for 8-week sustained response. New research observed fidaxomicin is superior to vancomycin in achieving desired clinical outcomes among patients with clostridioides difficile infection (CDI). In fact, the absolute … WebMedicare coverage and pricing details for Fidaxomicin. Learn more about Medicare prescription drug plans and savings with GoodRx. Type your drug name (like … submitting claims to medicare
Fidaxomicin versus Vancomycin for Clostridium difficile …
WebFidaxomicin is a substrate of P-gp. Co-administration of single doses of the P-gp inhibitor cyclosporine A and fidaxomicin in healthy volunteers, resulted in a 4- and 2-fold increase in fidaxomicin C max and AUC, respectively and in a 9.5 and 4-fold increase in C max and AUC, respectively, of the main active metabolite OP-1118. WebFeb 1, 2013 · A 10-day supply of fidaxomicin will cost approximately $3,360. It is significantly more expensive than metronidazole (about $35), commercially available oral … WebSignificantly fewer patients in the fidaxomicin group than in the vancomycin group had a recurrence of the infection, in both the modified intention-to-treat analysis (15.4% vs. 25.3%, P = 0.005 ... pain on top of shin bone under knee