Doxorubicin wavelength
WebWe showed that doxorubicin has a maximum excitation and emission wavelength of 470 and 560 nm, respectively. The detection sensitivity by fluorescence spectrometry is less … WebMay 31, 2024 · We analysed doxorubicin hydrochloride (Dox·HCl) and liposomal encapsulated doxorubicin hydrochloride (Dox·Lipo), two common drugs for anti-cancer treatment in clinical medicine. Optoacoustic measurements revealed a strong signal of both doxorubicin substrates at 488 nm excitation wavelength.
Doxorubicin wavelength
Did you know?
WebMay 12, 2024 · The wavelength of the excitation cytometer was 488 nm, and the DOX signal was detected with a filter having a wavelength greater than 560 nm. Measurement of apoptosis AnnexinV-FITC/PI double... WebNational Center for Biotechnology Information
WebCommon name (s): Doxorubicin : Dox : 10- [ (3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8- (hydroxyacetyl)-1-methoxy-, (8S,10S)-5,12-Naphthacenedione IUPAC name: CAS number: 23214-92-8 Chemical Formula: C27 H29 N O11 Molecular Weight: 543.53g / Mol Substance Class: … WebDec 6, 2024 · As the doxorubicin with anthracycline structure has a unique absorption at 480, we set the UV detector wavelength at 480 nm. Surprisingly, a plurality of peaks having ultraviolet absorption at 480 nm …
WebJan 2, 2024 · Lipid polymer hybrid nanoparticles (LPHNPs) for the controlled delivery of hydrophilic doxorubicin hydrochloride (DOX.HCl) ... All the spectra were recorded from 3,500 to 500 cm −1 wavelength, with 4 cm −1 resolution and 64 scans. Differential scanning calorimetry (DSC) WebApr 10, 2024 · Doxorubicin (DOX) is a widely employed anticancer drug containing a benzene ring. It is also used as an adjuvant chemotherapy drug for the postoperative treatment of melanoma. When DOX is loaded into the surface of nanofibers, an undesirable burst release is inevitable, causing severe side effects [ 38 , 39 ].
WebJul 15, 2024 · PDT and chemotherapy Drug: doxorubicin Wavelength: 589 nm: The combination of phototherapy and chemotherapy induced the expression of the key proteins of the mitochondria-mediated apoptosis pathway and exhibited a synergistic antitumor effect mediated by the mitochondrial-mediated apoptosis:
WebJun 1, 2016 · The maximum excitation wavelengths were both at 490 nm and the maximum emission wavelengths were obtained at 550 nm and 600 nm. After some pre-experiments, 550 nm was chosen for detection. All compounds provide sufficient and much better fluorescence to be detected and quantified. dallas jeep dealership txWebAug 21, 2013 · Doxorubicin, which is known to induce DNA damage predominantly in the G2/M phase of cell cycle , failed to show any activity at a low concentration of 0.01 µM. However, a significant G2/M arrest was induced by the same concentration of folate mediated micelles which was higher than that of micelles without folic acid ( Figure 9 ). dallas jenkins the chosen dvdWebA high-performance liquid chromatographic (HPLC) assay has been developed for the determination of the anticancer drug doxorubicin and the metabolites doxorubicinol, doxorubicinone, 7-deoxydoxorubicinone, doxorubicinolone and 7-deoxydoxorubicinolone in plasma of AIDS patients. dallas jenkins the chosen websiteWebNov 1, 2024 · The cardiotoxicity of doxorubicin limits its clinical utility as a cancer therapeutic. Abe et al. investigated how doxorubicin induces an iron-dependent form of cell death called ferroptosis specifically in … birchmount park torontoWebJul 25, 2024 · By encapsulating the doxorubicin (DOX) to the PEG-4-CyP NP (PEG-4-CyP/DOX), a conceptually new branched-form MDDS was constructed. After DOX encapsulation, it still showed redox-response to GSH by changing its absorption wavelength. At the same time, release of the drug was proven by collapse of the NP … birchmount plazabirchmount plaza scarboroughWebDoxorubicin and daunorubicin (internal standard, IS) were separated on a C (18) reversed-phase HPLC column and quantified by a fluoresence detection with an excitation wavelength of 475 nm and an emission wavelength of 580 nm. dallas jenkins the chosen cast