Clindamycin phosphate stable at ph
WebMar 1, 2024 · Clindamycin Phosphate Topical Solution, USP 1% contains clindamycin phosphate, USP, at a concentration equivalent to 10 mg clindamycin per milliliter. Clindamycin phosphate is a water … WebOct 28, 2024 · Clindamycin is an antibiotic that kills certain types of bacteria or stops them from growing. Doctors may prescribe this to kill Propionibacterium acnes ( P. acnes) bacteria that can lead to ...
Clindamycin phosphate stable at ph
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WebOct 20, 2008 · Abstract. The stability of clindamycin hydrochloride and clindamycin phosphate was studied in topical liquid formulations prepared with the following solvents: solvent A (70% isopropanol, 10% propylene … WebClindamycin phosphate is a water soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin. The chemical name for clindamycin phosphate is methyl 7-chloro-6,7,8 trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-α−. D ...
WebClindamycin phosphate should not be injected intravenously undiluted as a bolus, ... When necessary, pH is adjusted with sodium hydroxide and/or hydrochloric acid. Clindamycin Injection, USP is supplied in single dose vials as follows: NDC Vial Size Total Clindamycin Phosphate/vial; 72611-634-25 (carton contains 25 vials of 72611-634-01) WebClindamycin phosphate European Pharmacopoeia (EP) Reference Standard; CAS Number: 24729-96-2; EC Number: 246-433-0; Synonyms: Clindamycin 2 …
WebClindamycin phosphate is soluble in water. This solubility is pH dependent: at pH 7 the solubility is between 200 and 300 mg/ml, whereas at pH 4 it is 25 mg/ml. Clindamycin … WebJul 12, 2024 · Partition Coefficient: (Method, pH, Endpoint, Value) Decomposition Temperature (°C): No data available. _____ CLINDAMYCIN PHOSPHATE VAGINAL CREAM Polysorbate 60 Revision date: 12-Jul-2024 No data available Odor: No data available. Propylene glycol Material Name: Clindamycin Phosphate Vaginal Cream No …
Webclindamycin phosphate, which is a water-soluble ester of clindamycin and phosphoric acid and is used parenterally. Both the palmitic and the phos-phoric acid esters of clindamycin are inactive in vitro but are hydrolyzed to active clindamycin in vivo [24]. The unwary may use these ester forms in the laboratory for susceptibility testing and en-
WebClindamycin palmitate hydrochloride is freely soluble in water, in chloroform, in ether, and in benzene. It is soluble 1:3 in alcohol and 1:9 in ethyl acetate. It is very soluble in dimethylformamide. The pH of a 1% solution in water is between 2.8 and 3.8. Clindamycin phosphate is soluble 1:2.5 in water, slightly soluble in dehydrated alcohol ... dr chohan cardiologistWebMar 1, 2024 · Clindamycin Phosphate Topical Solution, USP 1% contains clindamycin phosphate, USP, at a concentration equivalent to 10 mg clindamycin per milliliter. Clindamycin phosphate is a water soluble … dr chohan buffalo nyWebthis, in a separate chromatographic run, solutions of both clindamycin phosphate and clindamycin hydrochloride (100 µg/ml each) were prepared in water and analysed using different chromatographic conditions. Chromatographic conditions consisted of a mobile phase made up of phosphate buffer (pH 3) and acetonitrile (70:30 v/v) at a flow rate of ... end of year parent survey questionsWebApr 1, 2024 · This medicine contains alcohol and is flammable. Do not use near heat, near open flame, or while smoking. To apply this medicine: Do not dispense clindamycin … end of year parent letterWebThe solution contains isopropyl alcohol 50% v/v, propylene glycol, and purified water. May contain sodium hydroxide for pH balance. The structural formula is represented below: … end of year organisational performance reportWebDec 20, 2024 · The pH of all hydrogel was in range 5.5–6.4 and viscosity was 2,017.03–3,866.52 cps. All the hydrogel was stable and diameter inhibition of hydrogel was in a range 20–32 mm. The amount of usnic acid in hydrogel was in range 96.9–99.23%. In conclusion, hydrogel UA-SD is promising preparation in handling acne. dr chohan eye clinic islamabadWebJan 1, 2007 · The predominant degradative routes of lincomycin-2-phosphate in the pH range 1-10 are thioglycoside and phosphate ester hydrolysis, and pH-rate studies show that it is most stable at pH 6-10 ... dr chohan fourways life